'bubble' children treatment hope 绝症儿童治疗有治愈希望-凯发k8官网

'bubble' children treatment hope 绝症儿童治疗有治愈希望
文章来源:未知 文章作者:meng 发布时间:2009-09-02 05:49 字体: [ ] 
(单词翻译:双击或拖选)

children seriously ill because their immune systems have 1 flaws could have their lives saved by a safer form of bone 2 transplant, doctors say.

医生称,因基因缺陷导致病重的儿童可以通过更为安全的骨髓移植的方法来治疗。

3 children have to live in 4 conditions" width="226" border="0" src="/upimg/090902/4_061012_1.jpg" />
without treatment, affected children have to live in sterile conditions

the london team says the treatment for so-called "bubble" children - who have to live in sterile(不毛的,不孕的) conditions - almost eliminates the need for chemotherapy(化学疗法).

the great ormond street doctors used antibodies to clear patient bone marrow(骨髓) and make room for 5 stem cells.

they report in the lancet the method cuts both 6 and side-effects.

high doses

chemotherapy has both short and long-term consequences, ranging from hair loss to damage to organs such as the liver and lungs.

but it has been used as standard to kill the patient's own bone marrow and make room for stem cells.

this treatment has saved the lives of many children with serious genetic defects in their immune systems - primary immunodeficiencies(免疫缺陷) or pid - that render(提供,报答) even the most 7 infections life-threatening.

fifty such transplants are carried out each year.

but some children are deemed too sick to withstand(抵抗,对抗) the high doses of drugs needed to wipe out the bone marrow.

gentler chemotherapy has been developed, but is still too much for certain groups of patients, such as babies.

sickest children

the new technique, developed by doctors from great ormond street and the ucl institute of child health, uses an antibody that targets a 8(分子) specific to blood and bone cells - meaning other tissues are left undamaged.

the team led by dr persis amrolia, reported that 13 of the 16 patients treated in the study had survived and been cured of their 9 disease.

they recovered twice as quickly as those given standard treatment, although there were still some complications.

"because this approach was experimental, we only used it on the sickest children, who we felt could not tolerate standard transplant chemotherapy.

"given how sick these children were before transplant, the results are remarkable," said dr amrolia.

"what's really encouraging is that pretty much all the children who survived now have a really good quality of life.

"there's still a lot to do and the challenge now is to develop similar targeted approaches for children with other genetic diseases and leukaemia(白血病)."

chris hughan, chief executive of the primary immunodeficiency association, said: "we welcome this important study as it 10(预报,宣布) a potential breakthrough in the treatment of paediatric(儿科的) pid patients who need a bone marrow transplant (bmt) but have significant 11 infection(慢性传染) or organ damage at the time.

the new treatment "provides a 12 alternative conditioning treatment for children unable to tolerate intensive transplant chemotherapy.

"we look forward to supporting this new bmt programme at gosh and making our members aware of this exciting new treatment development."



点击收听单词发音收听单词发音  

1 pgixp     
adj.遗传的,遗传学的
参考例句:
  • it's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
2 m2mye     
n.骨髓;精华;活力
参考例句:
  • it was so cold that he felt frozen to the marrow. 天气太冷了,他感到寒冷刺骨。
  • he was tired to the marrow of his bones.他真是累得筋疲力尽了。
3 tzuzg0     
adj.不自然的,假装的
参考例句:
  • she showed an affected interest in our subject.她假装对我们的课题感到兴趣。
  • his manners are affected.他的态度不自然。
4 ornyq     
adj.不毛的,不孕的,无菌的,枯燥的,贫瘠的
参考例句:
  • this top fits over the bottle and keeps the teat sterile.这个盖子严实地盖在奶瓶上,保持奶嘴无菌。
  • the farmers turned the sterile land into high fields.农民们把不毛之地变成了高产田。
5 dstxi     
n.捐献者;赠送人;(组织、器官等的)供体
参考例句:
  • in these cases,the recipient usually takes care of the donor afterwards.在这类情况下,接受捐献者以后通常会照顾捐赠者。
  • the doctor transplanted the donor's heart to mike's chest cavity.医生将捐赠者的心脏移植进麦克的胸腔。
6 fvpxp     
n.拒绝,被拒,抛弃,被弃
参考例句:
  • he decided not to approach her for fear of rejection.他因怕遭拒绝决定不再去找她。
  • the rejection plunged her into the dark depths of despair.遭到拒绝使她陷入了绝望的深渊。
7 e7fzr     
adj.较小(少)的,较次要的;n.辅修学科;vi.辅修
参考例句:
  • the young actor was given a minor part in the new play.年轻的男演员在这出新戏里被分派担任一个小角色。
  • i gave him a minor share of my wealth.我把小部分财产给了他。
8 y6tzn     
n.分子,克分子
参考例句:
  • a molecule of water is made up of two atoms of hygrogen and one atom of oxygen.一个水分子是由p妈?f婘??妈?成的。
  • this gives us the structural formula of the molecule.这种方式给出了分子的结构式。
9 5fyz8c     
adj.在下面的,含蓄的,潜在的
参考例句:
  • the underlying theme of the novel is very serious.小说隐含的主题是十分严肃的。
  • this word has its underlying meaning.这个单词有它潜在的含义。
10 85a7677643514d2e94585dc21f41b7ab     
n.使者( herald的名词复数 );预报者;预兆;传令官v.预示( herald的第三人称单数 );宣布(好或重要)
参考例句:
  • the song of birds heralds the approach of spring. 百鸟齐鸣报春到。 来自《现代英汉综合大词典》
  • the wind sweeping through the tower heralds a rising storm in the mountain. 山雨欲来风满楼。 来自《现代汉英综合大词典》
11 bo9zl     
adj.(疾病)长期未愈的,慢性的;极坏的
参考例句:
  • famine differs from chronic malnutrition.饥荒不同于慢性营养不良。
  • chronic poisoning may lead to death from inanition.慢性中毒也可能由虚弱导致死亡。
12 mi2wz     
adj.可行的,切实可行的,能活下去的
参考例句:
  • the scheme is economically viable.这个计划从经济效益来看是可行的。
  • the economy of the country is not viable.这个国家经济是难以维持的。
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tag标签: child genetic transplant
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