斯克里普斯研究所发现对付血癌的新方法-凯发k8官网

斯克里普斯研究所发现对付血癌的新方法

文章来源：未知文章作者：meng 发布时间：2009-12-01 00:38 字体： [ ]　

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a study led by a scripps research institute scientist describes a new, highly pragmatic approach（实际的方法） to the identification of ¹ that prevent a specific type of immune cells from attacking their host. the findings add a powerful new tool to the ² search for potential treatments for autoimmune（自身免疫的） diseases, such as multiple sclerosis (ms), as well as blood cancers, such as myeloid leukemia（骨髓性白血病）. the study by thomas kodadek, a professor in the chemistry and cancer biology departments at scripps florida, and colleagues was published in the november 25, 2009 issue (volume 16, issue 11) of the journal chemistry & biology.

in the new study, kodadek and his colleagues used samples from an animal model of multiple sclerosis（多发性硬化） to screen for t cells—a type of white blood cell that plays a central role in the immune system—with a heightened presence in the disease. the screen also identified molecules that ³ with these t cells' "autoreactivity," in other words, their attack on the body itself rather than a foreign ⁴ such as virus or bacteria.

"our technique ⁵ uncovers and ⁶ autoreactive t cells as well as inhibitors（禁制因素） to them," kodadek said. "it's a double whammy（祸不单行）. at the heart of this is a comparative screening process of normal t cells ⁸ disease-causing t cells. while the process is ⁹ complicated and difficult, the thinking behind it is not. we wanted to simplify the process of identifying compounds that could ⁷ autoreactive t cells with exceptional specificity, and we succeeded."

the scientists used a model of ms, an autoimmune inflammatory disease（炎性疾病） affecting the brain and ¹⁰ cord（脊髓）, for the study. in ms, the immune system attacks the myelin sheath（髓鞘） covering and protecting nerve cells, leading to a variety of symptoms depending on which part of the nervous system is ¹¹. common symptoms of the condition include fatigue（疲乏，疲劳）; ¹²（麻木）; walking, balance, and ¹³ problems（协调问题）; bladder（膀胱） and ¹⁴（肠） dysfunction; vision problems; dizziness and ¹⁵（眩晕）; sexual dysfunction; pain; ¹⁶ problems; emotional changes; and spasticity（痉挛）.

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1
分子( molecule的名词复数 )
参考例句：
the structure of molecules can be seen under an electron microscope. 分子的结构可在电子显微镜下观察到。 inside the reactor the large molecules are cracked into smaller molecules. 在反应堆里，大分子裂变为小分子。

2
adj.进行中的，前进的
参考例句：
the problem is ongoing.这个问题尚未解决。 the issues raised in the report relate directly to age concern's ongoing work in this area.报告中提出的问题与“关心老人”组织在这方面正在做的工作有直接的关系。

3
v.(in)干涉，干预；(with)妨碍，打扰
参考例句：
if we interfere, it may do more harm than good.如果我们干预的话，可能弊多利少。 when others interfere in the affair,it always makes troubles. 别人一卷入这一事件，棘手的事情就来了。

4
n.侵略者，侵犯者，入侵者
参考例句：
they suffered a lot under the invader's heel.在侵略者的铁蹄下，他们受尽了奴役。 a country must have the will to repel any invader.一个国家得有决心击退任何入侵者。

5
adv.同时发生地，同时进行地
参考例句：
the radar beam can track a number of targets almost simultaneously.雷达波几乎可以同时追着多个目标。 the windows allow a computer user to execute multiple programs simultaneously.windows允许计算机用户同时运行多个程序。

6
v.使隔离( isolate的第三人称单数 )；将…剔出（以便看清和单独处理）；使（某物质、细胞等）分离；使离析
参考例句：
the transformer isolates the transistors with regard to d-c bias voltage. 变压器可在两个晶体管之间隔离直流偏压。来自辞典例句 in regions with certain isolates of trv, spraining is more prominent. 在具有trv某些分离物的地区，坏死是比较显著的。来自辞典例句

7
vt.阻止，妨碍，抑制
参考例句：
don't let ego and greed inhibit clear thinking and hard work.不要让自我和贪婪妨碍清晰的思维和刻苦的工作。 they passed a law to inhibit people from parking in the street.他们通过一项法令以阻止人们在街上停车。

8
prep.以…为对手，对；与…相比之下
参考例句：
the big match tonight is england versus spain.今晚的大赛是英格兰对西班牙。 the most exciting game was harvard versus yale.最富紧张刺激的球赛是哈佛队对耶鲁队。

9
adv.专门地，技术上地
参考例句：
technically it is the most advanced equipment ever.从技术上说，这是最先进的设备。 the tomato is technically a fruit,although it is eaten as a vegetable.严格地说，西红柿是一种水果，尽管它是当作蔬菜吃的。

10
adj.针的，尖刺的，尖刺状突起的；adj.脊骨的，脊髓的
参考例句：
after three days in japan,the spinal column becomes extraordinarily flexible.在日本三天，就已经使脊椎骨变得富有弹性了。 your spinal column is made up of 24 movable vertebrae.你的脊柱由24个活动的脊椎骨构成。

11
adj.不自然的，假装的
参考例句：
she showed an affected interest in our subject.她假装对我们的课题感到兴趣。 his manners are affected.他的态度不自然。

12
n.无感觉，麻木，惊呆
参考例句：
she was fighting off the numbness of frostbite. 她在竭力摆脱冻僵的感觉。来自《简明英汉词典》 sometimes they stay dead, causing' only numbness. 有时，它们没有任何反应，只会造成麻木。来自时文部分

13
n.协调，协作
参考例句：
gymnastics is a sport that requires a considerable level of coordination.体操是一项需要高协调性的运动。 the perfect coordination of the dancers and singers added a rhythmic charm to the performance.舞蹈演员和歌手们配合得很好，使演出更具魅力。

14
n.肠(尤指人肠)；内部，深处
参考例句：
irritable bowel syndrome seems to affect more women than men.女性比男性更易患肠易激综合征。 have you had a bowel movement today?你今天有排便吗？

15
n.眩晕
参考例句：
he had a dreadful attack of vertigo.他忽然头晕得厉害。 if you have vertigo it seems as if the whole room is spinning round you.如果你头晕，就会觉得整个房间都旋转起来

16
adj.认知的，认识的，有感知的
参考例句：
as children grow older,their cognitive processes become sharper.孩子们越长越大，他们的认知过程变得更为敏锐。 the cognitive psychologist is like the tinker who wants to know how a clock works.认知心理学者倒很像一个需要通晓钟表如何运转的钟表修理匠。