肠道细菌可能是代谢健康的关键因素-凯发k8官网

肠道细菌可能是代谢健康的关键因素
文章来源:未知 文章作者:enread 发布时间:2015-06-23 06:26 字体: [ ] 
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the 1 microbe akkermansia muciniphila may hold the key to better 2 health and healthier body fat distribution in people who are overweight or 3, reveals a small study published online in the journal gut. the microbe seems to be linked to lower levels of fasting blood 4 and fats--key factors involved in the development of 5 and heart disease--and healthier distribution of body fat, the findings indicate.
 
in healthy people a. muciniphila makes up around 3-5% of the gut's 6 7 and is associated with a diet rich in insoluble fibre.
 
the evidence to date suggests that a wide range of gut microbes and the chemical processes that sustain life--8--have an important role in the development of 9 and potentially harmful metabolic 10.
 
a. muciniphila has already been linked to healthier glucose metabolism and leanness in mice, but it has not been clear whether this also applies to people.
 
the researchers therefore wanted to find out if the microbe was linked to bacterial diversity in the gut and a lower health risk profile in people who were overweight/obese.
 
they assessed levels of gut a. muciniphila and other bacteria, as well as fasting blood glucose and blood fats, and 11 of body fat distribution--waist:hip ratio and the amount of fat beneath the skin--in 49 obese or overweight adults.
 
these 12 were made before and after a dietary 13: 6 weeks of a low calorie diet with extra protein and fibre followed by 6 weeks of a stabilisation diet. calorie 14 is known to alter the composition of gut bacteria.
 
they found that at the start of the dietary intervention, those with evidence of abundant a. muciniphila in their 15 had lower fasting blood glucose and insulin levels, a smaller waist:hip ratio, and a smaller fat cell volume beneath their skin than those with low levels of the microbe.
 
those who had abundant a. muciniphila as well as a greater diversity of microbes in their gut to start with, had the healthiest metabolic profile--particularly for fasting blood glucose, triglycerides (blood fats), and body fat distribution.
 
after 6 weeks of calorie restriction, those with a greater abundance of a. muciniphila to start with showed stronger improvement in their metabolic profile and body fat distribution than those with lower levels.
 
calorie restriction was associated with a reduction in the abundance of a. muciniphila across the board, but these levels still remained 100 times higher in people in whom the microbe was more abundant to start with.
 
the researchers suggest that the by-products of a. muciniphila may act as a fuel for other beneficial gut bacteria.


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1 mezzp     
n.[pl.]胆量;内脏;adj.本能的;vt.取出内脏
参考例句:
  • it is not always necessary to gut the fish prior to freezing.冷冻鱼之前并不总是需要先把内脏掏空。
  • my immediate gut feeling was to refuse.我本能的直接反应是拒绝。
2 2r4z1     
adj.新陈代谢的
参考例句:
  • impressive metabolic alternations have been undergone during embryogenesis.在胚胎发生期间经历了深刻的代谢变化。
  • a number of intoxicants are associated with metabolic acidosis.许多毒性物质可引起代谢性酸中毒。
3 uviya     
adj.过度肥胖的,肥大的
参考例句:
  • the old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • being obese and lazy is dangerous to health.又胖又懒危害健康。
4 fyiyz     
n.葡萄糖
参考例句:
  • i gave him an extra dose of glucose to pep him up.我给他多注射了一剂葡萄糖以增强他的活力。
  • the doctor injected glucose into his patient's veins.医生将葡萄糖注入病人的静脉。
5 upnzu     
n.糖尿病
参考例句:
  • in case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。
6 dy5z8q     
a.细菌的
参考例句:
  • bacterial reproduction is accelerated in weightless space. 在失重的空间,细菌繁殖加快了。
  • brain lesions can be caused by bacterial infections. 大脑损伤可能由细菌感染引起。
7 wq4xz     
n.生态系统
参考例句:
  • this destroyed the ecosystem of the island.这样破坏了岛上的生态系统。
  • we all have an interest in maintaining the integrity of the ecosystem.维持生态系统的完整是我们共同的利益。
8 171zc     
n.新陈代谢
参考例句:
  • after years of dieting,carol's metabolism was completely out of whack.经过数年的节食,卡罗尔的新陈代谢完全紊乱了。
  • all living matter undergoes a process of metabolism.生物都有新陈代谢。
9 dv1ya     
n.肥胖,肥大
参考例句:
  • one effect of overeating may be obesity.吃得过多能导致肥胖。
  • sugar and fat can more easily lead to obesity than some other foods.糖和脂肪比其他食物更容易导致肥胖。
10 6e49dcafe3638183c823d3aa5b12b010     
n.混乱( disorder的名词复数 );凌乱;骚乱;(身心、机能)失调
参考例句:
  • reports of anorexia and other eating disorders are on the increase. 据报告,厌食症和其他饮食方面的功能紊乱发生率正在不断增长。 来自《简明英汉词典》
  • the announcement led to violent civil disorders. 这项宣布引起剧烈的骚乱。 来自《简明英汉词典》
11 f46872fc1b5f08e9d32bd107be1df829     
(仪器上显示温度、压力、耗油量等的)指针( indicator的名词复数 ); 指示物; (车辆上的)转弯指示灯; 指示信号
参考例句:
  • the economic indicators are better than expected. 经济指标比预期的好。
  • it is still difficult to develop indicators for many concepts used in social science. 为社会科学领域的许多概念确立一个指标仍然很难。
12 7d0657785d6e5832f8576c61c78262ef     
n.评估( assessment的名词复数 );评价;(应偿付金额的)估定;(为征税对财产所作的)估价
参考例句:
  • he was shrewd in his personal assessments. 他总能对人作出精明的评价。 来自《简明英汉词典》
  • surveys show about two-thirds use such assessments, while half employ personality tests. 调查表明,约有三分之二的公司采用了这种测评;而一半的公司则采用工作人员个人品质测试。 来自百科语句
13 e5sxz     
n.介入,干涉,干预
参考例句:
  • the government's intervention in this dispute will not help.政府对这场争论的干预不会起作用。
  • many people felt he would be hostile to the idea of foreign intervention.许多人觉得他会反对外来干预。
14 jw8x0     
n.限制,约束
参考例句:
  • the park is open to the public without restriction.这个公园对公众开放,没有任何限制。
  • the 30 mph speed restriction applies in all built-up areas.每小时限速30英里适用于所有建筑物聚集区。
15 yraziv     
v.狼吞虎咽,贪婪地吃,飞碟游戏(比赛双方每组5人,相距15码,互相掷接飞碟);毁坏(建筑物等)的内部( gut的第三人称单数 );取出…的内脏n.勇气( gut的名词复数 );内脏;消化道的下段;肠
参考例句:
  • i'll only cook fish if the guts have been removed. 鱼若已收拾干净,我只需烧一下即可。
  • barbara hasn't got the guts to leave her mother. 巴巴拉没有勇气离开她妈妈。 来自《简明英汉词典》
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