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the world health organization is pausing the use of hydroxychloroquine in its global study of covid-19 treatments amid a review of safety data, officials announced monday.
周一,世界卫生组织官员宣布,审查安全数据期间,在对新冠病毒疗法的全球研究中暂停使用羟氯喹。
the move follows findings from a large observational study, published friday, that found increased risk of heart problems and death in covid-19 patients who used chloroquine and hydroxychloroquine.
此前,在周五发表的一项大型观察性研究中发现,使用氯喹和羟氯喹的新冠病人患心脏病和死亡的风险会增加,因此做出这一决定。
it's a scientific decision nonetheless 1 with politics: u.s. president donald 2 is a champion of hydroxychloroquine, revealing last week that he's taking it to prevent covid-19. he has threatened to cut off u.s. funding to the who within a month absent unspecified reforms.
尽管如此,但这一科学决定充满政治因素:美国总统唐纳德·特朗普支持羟氯喹,他上周说正在吃羟氯喹来预防感染新冠病毒。他威胁说,如果不进行具体改革,将在一个月内切断美国对世界卫生组织的资金支持。
the executive committee of the who's 3 trial met last saturday, said who chief scientist soumya swaminathan, and 4 "in the light of this 5 that we should be proactive, 6 on the side of caution and suspend 7 temporarily into the hydroxychloroquine arm." (chloroquine is not part of the trial.)
世界卫生组织首席科学家soumya swaminathan说,世界卫生组织的solidarity临床试验执行委员会上周召开会议,决定“鉴于这种不确定性,我们要有前瞻性,谨慎行事,暂停使用羟氯喹”。(氯喹并不是此次试验用药。)
the meeting came a day after the lancet published the largest observational study of the 8 drugs to date, and as some national regulators began expressing concern about using the drug.
会议召开前一天,《柳叶刀》发表了迄今针对疟疾药物最大的观察性研究,一些国家监管机构开始表现出对使用这种药物的担忧。
who officials estimated the pause would last a week or two as the trial's data safety monitoring board considers information already collected from the solidarity trial and other 9 studies to determine whether it's safe to continue with hydroxychloroquine.
世界卫生组织官员估计暂停会持续一至两周,因为试验数据安全监测委员会要参考从solidarity临床试验和其他进行中的研究中所收集的信息,从而确定继续使用羟氯喹是否安全。
the study, a randomized trial, has 10 3,500 patients in at least 17 countries since march to study four medicines, including hydroxychloroquine.
这项研究是随机试验,从三月份开始在至少17个国家召集了3,500名患者来研究4种药物,其中就包括羟氯喹。
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