obesity drug fears investigated 美国调查某减肥药副作用-凯发k8官网

obesity drug fears investigated 美国调查某减肥药副作用
文章来源:未知 文章作者:meng 发布时间:2009-08-26 07:20 字体: [ ] 
(单词翻译:双击或拖选)

us authorities are investigating concerns an anti-obesity drug widely available over the counter at chemists may cause liver damage.

美国当局正在调查一种柜台上可轻易得到减肥药,据说这种药可能造成肝脏损伤。

trials suggests orlistat can help people lose 50% more weight
trials suggests orlistat can help people lose 50% more weight

orlistat went on sale under the brand name alli without the need for a 1(药方) in the uk in april.

the us food and drug administration has received more than 30 reports linking the drug to serious liver injury.

however, manufacturer glaxosmithkline said there was no evidence the drug caused liver damage.

in six of the cases reported to the fda patients went on to develop organ failure.

the pill, which works by blocking the absorption(吸收) of fat in the body, is aimed at adults with a body mass index (bmi) of 28 or more. it is also available on prescription as xenical.

clinical trials suggest adding orlistat to a reduced-calorie, lower-fat diet, can help people lose 50% more weight than dieting alone.

big sales

since going on sale at uk 2 around 200,000 people have bought the drug.

diarrhoea and gas problems are to be expected if users persist in eating fat while taking the drug.

however, concerns have been raised over the medication's other possible side-effects.

the fda said the most commonly reported 3 reactions(有害反应,逆反应) included the yellowing of skin or whites of the eyes, weakness and stomach pain.

between 1999 and 2008, the agency received 32 reports of liver damage, 30 of which occurred outside the us. of these 27 resulted in hospitalisation.

the agency said it was now conducting a review of the safety of the drug, but stressed no definite association with liver damage had been established at this stage.

it advised people who used orlistat to seek medical advice if they experience possible symptoms of liver injury, in particular weakness or 4(疲乏,疲劳), fever, jaundice(黄疸,偏见), or brown urine.

other symptoms may include 5 pain(腹痛), 6(反胃), 7, light-colored stools, 8, or loss of appetite.

however, the number of reports of liver damage is very small when compared with the many thousands of people who have used the drug.

experts also stressed that it is possible that many 9 people have 10 physical problems which could increase their risk of liver damage.

safety a priority

in the uk, the medicines and healthcare products regulatory agency (mhra) said it had received a total of 1,295 suspected adverse(不利的) drug reaction reports associated with orlistat, including 137 involving suspected liver damage, since it was 11 in 1998.

the european medicines agency said there was no plan to change the product information at present - but the situation was under review.

in a statement, glaxosmithkline (gsk) said patient safety was its top priority, and reports of side effects were constantly monitored.

the statement went on to say the drug had been extensively tested in clinical trials involving 30,000 patients.

"alli is a 'non-systemically' 12 medicine - it is 13 absorbed in the blood and works locally in the gastro-intestinal 14.

"there is therefore no obvious biological 15 to suggest liver damage can occur with alli."



点击收听单词发音收听单词发音  

1 u1vza     
n.处方,开药;指示,规定
参考例句:
  • the physician made a prescription against sea- sickness for him.医生给他开了个治晕船的药方。
  • the drug is available on prescription only.这种药只能凭处方购买。
2 a19950a91ea1800ed5273a89663d2855     
药店
参考例句:
  • still, 32 percent of the pharmacies filled the prescriptions. 但仍然有32%的药剂师配发了这两张药方。 来自互联网
  • chinese herbal pharmacies, and traditional massage therapists in the vancouver telephone book. 中药店,和传统的按摩师在温哥华的电话簿里。 来自互联网
3 5xbzs     
adj.不利的;有害的;敌对的,不友好的
参考例句:
  • he is adverse to going abroad.他反对出国。
  • the improper use of medicine could lead to severe adverse reactions.用药不当会产生严重的不良反应。
4 phvzv     
n.疲劳,劳累
参考例句:
  • the old lady can't bear the fatigue of a long journey.这位老妇人不能忍受长途旅行的疲劳。
  • i have got over my weakness and fatigue.我已从虚弱和疲劳中恢复过来了。
5 viuya     
adj.腹(部)的,下腹的;n.腹肌
参考例句:
  • the abdominal aorta is normally smaller than the thoracic aorta.腹主动脉一般比胸主动脉小。
  • abdominal tissues sometimes adhere after an operation.手术之后腹部有时会出现粘连。
6 c5dzz     
n.作呕,恶心;极端的憎恶(或厌恶)
参考例句:
  • early pregnancy is often accompanied by nausea.怀孕期常有恶心的现象。
  • he experienced nausea after eating octopus.吃了章鱼后他感到恶心。
7 7ed7266d85c55ba00ffa41473cf6744f     
参考例句:
  • symptoms include diarrhoea and vomiting. 症状有腹泻和呕吐。
  • especially when i feel seasick, i can't stand watching someone else vomiting." 尤其晕船的时候,看不得人家呕。”
8 wqnzvz     
adj.贪得的,痒的,渴望的v.发痒( itch的现在分词 )
参考例句:
  • the itching was almost more than he could stand. 他痒得几乎忍不住了。 来自《现代汉英综合大词典》
  • my nose is itching. 我的鼻子发痒。 来自《简明英汉词典》
9 uviya     
adj.过度肥胖的,肥大的
参考例句:
  • the old man is really obese,it can't be healthy.那位老人确实过于肥胖了,不能算是健康。
  • being obese and lazy is dangerous to health.又胖又懒危害健康。
10 5fyz8c     
adj.在下面的,含蓄的,潜在的
参考例句:
  • the underlying theme of the novel is very serious.小说隐含的主题是十分严肃的。
  • this word has its underlying meaning.这个单词有它潜在的含义。
11 ipmzni     
adj.得到许可的v.许可,颁发执照(license的过去式和过去分词)
参考例句:
  • the new drug has not yet been licensed in the us. 这种新药尚未在美国获得许可。
  • is that gun licensed? 那支枪有持枪执照吗?
12 czrzoc     
n.演戏,行为,假装;adj.代理的,临时的,演出用的
参考例句:
  • ignore her,she's just acting.别理她,她只是假装的。
  • during the seventies,her acting career was in eclipse.在七十年代,她的表演生涯黯然失色。
13 0e3844f43172f471e75a897f7b3116da     
最低限度地,最低程度地
参考例句:
  • food spoilage problems occur with minimally processed, concentrated frozen citrus products. 食品的变质也发生在轻微加工的、浓缩冷冻的柑橘制品中。
  • so, minimally, they are responsible for such actions and omissions. 所以,至少来说,他们要对这样的行为和忽略负责。
14 ijxz4     
n.传单,小册子,大片(土地或森林)
参考例句:
  • he owns a large tract of forest.他拥有一大片森林。
  • he wrote a tract on this subject.他曾对此写了一篇短文。
15 zcwxr     
n.机械装置;机构,结构
参考例句:
  • the bones and muscles are parts of the mechanism of the body.骨骼和肌肉是人体的组成部件。
  • the mechanism of the machine is very complicated.这台机器的结构是非常复杂的。
tag标签: drug investigate
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